https://scholars.lib.ntu.edu.tw/handle/123456789/629954
標題: | Enhancing the insecticidal potential of a baculovirus by overexpressing the mammalian β-galactosyl binding protein galectin-1 | 作者: | Lin, Chia-Yang Lin, Yu-Hsien Lin, Yu-Chun Hsu, Chun-Min YUEH-LUNG WU RONG-NAN HUANG |
關鍵字: | baculovirus; bio-control; galectin-1; β-galactosyl-binding protein | 公開日期: | 二月-2023 | 出版社: | JOHN WILEY & SONS LTD | 卷: | 79 | 期: | 2 | 起(迄)頁: | 701 | 來源出版物: | Pest management science | 摘要: | Bio-pesticide development is an important area of research in agriculture, in which viruses are an essential tool. Infection by entomological pathogenic viruses kills agricultural pests, and viral progenies are disseminated to infect more pests, eventually achieving long-term pest control in the field. Of the current virus-based pest control models, Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is the most studied. AcMNPV belongs to the Baculoviridae family and can infect many lepidopterans. Although AcMNPV has been previously demonstrated to be a potential pest-control tool, its long virus infection cycle has made field applications challenging. To overcome this, we generated a recombinant baculovirus that can express mammalian galectin-1, which is a galactoside-binding protein that binds to the peritrophic matrix in the midgut of lepidopteran pests and induces perforation of the membrane. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/629954 | ISSN: | 1526-498X | DOI: | 10.1002/ps.7237 |
顯示於: | 昆蟲學系 |
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