https://scholars.lib.ntu.edu.tw/handle/123456789/630183
Title: | Relationship between Atrial Tachyarrhythmias and Intrathoracic Impedance in Patients with a Pacemaker and Preserved Ejection Fraction | Authors: | MIN-TSUN LIAO CHUN-KAI CHEN TING TSE LIN Cheng, Li-Ying Ting, Hong-Wen Wang, Rou-Fang Liu, Zhi-Jun YEN BIN LIU |
Keywords: | OptiVol fluid index;atrial tachyarrhythmias;intrathoracic impedance | Issue Date: | 31-Dec-2019 | Publisher: | MDPI | Journal Volume: | 9 | Journal Issue: | 1 | Start page/Pages: | 105 | Source: | Journal of clinical medicine | Abstract: | Atrial fibrillation (AF) is responsible for significant morbidity and mortality in patients with heart failure (HF). Modern pacemakers provide an index of intrathoracic fluid status (OptiVol fluid index-OVFI) by measuring daily intrathoracic impedance. This study aimed to determine whether OVFI is associated with increased atrial tachycardia/fibrillation (AT/AF) events in patients with a preserved ejection fraction (EF). We retrospectively reviewed data from patients with Medtronic Advisa pacemakers between 2012 and 2014 in our hospital. The association and temporal relationship between OVFI and AT/AF events were determined. A total of 150 patients with 211 follow-up visits (mean 1.4 visits per patient) were evaluated. The device-detected AT/AF prevalence was 47%. Device-measured OVFI ≥ 20 Ω-days was significantly associated with the onset of AT/AF ≥ 4 h. OVFI threshold crossing preceded AT/AF events in 55.1% of cases, followed by AT/AF events in only 18.7%. Fluid overload represented by OVFI may trigger AT/AF episodes in patients with a preserved EF more often than that previously reported in patients with a reduced EF. Our findings support the view that worsening pulmonary congestion is associated with increased AT/AF frequency and suggests that fluid overload could trigger and perpetuate AT/AF events in patients with a preserved EF. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630183 | ISSN: | 2077-0383 | DOI: | 10.3390/jcm9010105 |
Appears in Collections: | 醫學系 |
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