Characterization of Hepatitis B Virus in Tenofovir-Treated and Untreated Chronically Infected Mothers and Their Immunoprophylaxis Failure Infants
Journal
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Journal Volume
76
Journal Issue
3
Pages
e783
Date Issued
2023-02-08
Author(s)
Chiang, Cheng-Lun
Lai, Ming-Wei
Mu, Shu-Chi
Wen, Wan-Hsin
Cheng, Shao-Wen
Hu, Jen-Jan
Abstract
Maternal tenofovir disoproxil fumarate (TDF) therapy during late pregnancy can reduce mother-to-infant transmission of hepatitis B virus (HBV). We investigated HBV mutations associated with maternal TDF therapy and their role in infant immunonophylaxis failure (IPF).
Subjects
HBV carriers; HBV genetic variation; antiviral therapy; immunoprophylaxis failure infants; pregnant women
Publisher
OXFORD UNIV PRESS INC
Type
journal article