https://scholars.lib.ntu.edu.tw/handle/123456789/630356
Title: | Interleukin 28B genetic polymorphisms play a minor role in identifying optimal treatment duration in HCV genotype 1 slow responders to pegylated interferon plus ribavirin | Authors: | CHEN-HUA LIU Liang, Cheng-Chao CHUN-JEN LIU TAI-CHUNG TSENG Lin, Chih-Lin Yang, Sheng-Shun TUNG-HUNG SU JOU-WEI LIN Chen, Jun-Herng PEI-JER CHEN DING-SHINN CHEN JIA-HORNG KAO |
Keywords: | CHRONIC HEPATITIS-C; PEGINTERFERON ALPHA-2B; VIROLOGICAL RESPONSE; COMBINATION THERAPY; IL28B; TELAPREVIR; BOCEPREVIR; DIAGNOSIS; FIBROSIS | Issue Date: | 2012 | Publisher: | INT MEDICAL PRESS LTD | Journal Volume: | 17 | Journal Issue: | 6 | Start page/Pages: | 1059 | Source: | Antiviral therapy | Abstract: | Pegylated interferon and ribavirin for 72 weeks improve sustained virological response (SVR) in HCV genotype 1 (HCV-1) slow viral responders. Whether interleukin 28B (IL28B) single nucleotide polymorphism (SNP) genotypes and on-treatment viral responses can identify non-rapid virological response (RVR) patients who benefit from 48 or 72 weeks of therapy remains unclear. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630356 | ISSN: | 1359-6535 | DOI: | 10.3851/IMP2322 |
Appears in Collections: | 醫學系 |
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