https://scholars.lib.ntu.edu.tw/handle/123456789/630363
標題: | Monitoring of T790M in plasma ctDNA of advanced EGFR-mutant NSCLC patients on first- or second-generation tyrosine kinase inhibitors | 作者: | CHUN-TA HUANG Lin, Chih-An Su, Te-Jen CHING-YAO YANG TZU-HSIU TSAI CHIA-LIN HSU WEI-YU LIAO KUAN-YU CHEN CHAO-CHI HO CHONG-JEN YU |
關鍵字: | Droplet digital polymerase chain reaction; EGFR mutation; Lung cancer; Osimertinib; Tyrosine kinase inhibitor | 公開日期: | 13-三月-2023 | 出版社: | BMC | 卷: | 23 | 期: | 1 | 來源出版物: | BMC cancer | 摘要: | The T790M mutation is the major resistance mechanism to first- and second-generation TKIs in EGFR-mutant NSCLC. This study aimed to investigate the utility of droplet digital PCR (ddPCR) for detection of T790M in plasma circulating tumor DNA (ctDNA), and explore its impact on prognosis. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630363 | ISSN: | 1471-2407 | DOI: | 10.1186/s12885-023-10698-5 |
顯示於: | 醫學系 |
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