https://scholars.lib.ntu.edu.tw/handle/123456789/630438
標題: | The Sequential Change in Left Ventricular Function among Various Cardiovascular Diseases: A 12-Year Study | 作者: | SHENG-NAN CHANG JOU-WEI LIN YI-CHIH WANG CHO-KAI WU Cheng, Jun-Jack JUEY-JEN HWANG JIUNN-LEE LIN FU-TIEN CHIANG YIH-SHARNG CHEN RON-BIN HSU Chen, William Chen, Jin-Jer Lien, Wen-Pin |
關鍵字: | 2-dimensional echocardiography; coronary artery disease; diastolic function; elderly; hypertension; integrated score index; tissue Doppler imaging | 公開日期: | 7-三月-2022 | 出版社: | MDPI | 卷: | 12 | 期: | 3 | 起(迄)頁: | 415 | 來源出版物: | Journal of personalized medicine | 摘要: | Background: This 12-year study aimed to compare the longitudinal change in left ventricular diastolic dysfunction (LVDD) between healthy elderly, coronary artery disease (CAD), and hypertension (HTN) patients. Methods: From 2008 to 2020, 1476 patients were included, and 3181 echocardiography examinations were conducted. Finally, 130 participants (36 healthy elderly (79.39 ± 9.51 years old), 51 with CAD (68.31 ± 12.09 years old), and 43 with HTN (68.31 ± 12.09 years old)) with more than a 10-year follow-up period were included in the final analysis. Results: The change in diastolic function was different among these subjects according to the integrated score index (elderly vs. HTN, p = 0.01; CAD vs. HTN, p = 0.01), septal E/e′ ratio (elderly vs. HTN, p < 0.001; CAD vs. HTN, p = 0.01), lateral E/e′ ratio (elderly vs. HTN, p < 0.001; CAD vs. HTN, p < 0.001), and NYHA functional class (elderly vs. HTN, p = 0.03; CAD vs. HTN, p < 0.001). Additionally, per one-year increase in age, the integrated score index increased 0.2 in the healthy elderly, 0.15 in the CAD, and 0.06 in the HTN patients (all p < 0.05). Conclusion: Under aggressive treatment, diastolic function was relatively preserved in HTN subjects with aging in comparison with elderly and CAD subjects. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/630438 | ISSN: | 2075-4426 | DOI: | 10.3390/jpm12030415 |
顯示於: | 醫學系 |
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