https://scholars.lib.ntu.edu.tw/handle/123456789/631242
標題: | Heavy metal-free electrochemical detection of pyrophosphate ions by Nafion/carbon dots decorated screen printed carbon electrodes | 作者: | Chang, CW WEI-SSU LIAO |
關鍵字: | carbon dot; electrochemical; pyrophosphate ion; screen printed carbon electrode; sensor; INORGANIC PYROPHOSPHATE; ALKALINE-PHOSPHATASE; SELECTIVE DETECTION; QUANTUM DOTS; SENSOR; WATER; PPI; CHEMOSENSOR; POLYMER; PROBE | 公開日期: | 2023 | 出版社: | WILEY-V C H VERLAG GMBH | 來源出版物: | JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 摘要: | We employ Nafion-mixed carbon dots (CDs) and low-cost screen-printed carbon electrodes (SPCEs) as foundation matrices for the fabrication of electrochemical biosensors. The -NH2 and -COOH functional groups present on the SPCE surface after Nafion/CDs deposition allow for pyrophosphate ions (PPis) collection. Using Fe(CN)63− as the electrochemical mediator, the SPCE-Nafion/CDs are applied to the detection of aqueous PPi by square wave voltammetry. Between 50 and 1 μM, a linear connection is established between the square wave voltammetry current and the PPi concentration. The limit of detection is determined to be 1.01 μM, and recoveries of 113% (±1.9%) and 108% (±3.9%) are achieved for human urine samples spiked with 6 and 3 μM of PPi, respectively. Furthermore, this PPi assay is suitable for the usage of complicated urine matrices without the inclusion of heavy metals. We anticipate that this unique approach will be beneficial for PPi level monitoring in urine during therapeutic treatments of illnesses and malignancies. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/631242 | ISSN: | 0009-4536 | DOI: | 10.1002/jccs.202300064 |
顯示於: | 化學系 |
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