https://scholars.lib.ntu.edu.tw/handle/123456789/631382
標題: | High-throughput screening of chemical libraries for modulators of gene promoter activity of HLA-B2705: environmental pathogenesis and therapeutics of ankylosing spondylitis | 作者: | Zhao, Like CHIN-HSIU LIU Yu, David |
關鍵字: | ANKYLOSING SPONDYLITIS; FLAVONOID; LEI GONG TENG; NATURAL PRODUCTS; ENVIRONMENTAL PATHOGENESIS; WILFORDII HOOK-F; NF-KAPPA-B; RHEUMATOID-ARTHRITIS; NUCLEAR-FACTOR; DOUBLE-BLIND; RED-CLOVER; FLAVONOIDS; CHEMISTRY; INHIBITION; APIGENIN | 公開日期: | 六月-2011 | 出版社: | J RHEUMATOL PUBL CO | 卷: | 38 | 期: | 6 | 起(迄)頁: | 1061 | 來源出版物: | The Journal of rheumatology | 摘要: | Ankylosing spondylitis (AS) is a highly heritable disease with HLA-B27 being the strongest susceptible gene. In order to survey the environmental triggers for arthritis development, we used a high-throughput technique to screen the effects of 12,264 chemicals on the HLA-B27 gene promoter. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/631382 | ISSN: | 0315-162X | DOI: | 10.3899/jrheum.101109 |
顯示於: | 醫學系 |
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