Completion, safety, and efficacy of tuberculosis preventive treatment regimens containing rifampicin or rifapentine: an individual patient data network meta-analysis
Journal
The Lancet. Respiratory medicine
Date Issued
2023-03-23
Author(s)
Winters, Nicholas
Belknap, Robert
Benedetti, Andrea
Borisov, Andrey
Campbell, Jonathon R
Chaisson, Richard E
Chan, Pei-Chun
Martinson, Neil
Nahid, Payam
Scott, Nigel A
Sizemore, Erin
Sterling, Timothy R
Villarino, M Elsa
Menzies, Dick
Abstract
3 months of weekly rifapentine plus isoniazid (3HP) and 4 months of daily rifampicin (4R) are recommended for tuberculosis preventive treatment. As these regimens have not been compared directly, we used individual patient data and network meta-analysis methods to compare completion, safety, and efficacy between 3HP and 4R.
SDGs
Type
journal article