https://scholars.lib.ntu.edu.tw/handle/123456789/631756
標題: | Analytical Technology for Single-Cancer-Cell Analysis | 作者: | Kuo, Ching Te HSIN-YU LEE |
公開日期: | 1-一月-2021 | 出版社: | Springer Singapore | 起(迄)頁: | 851 - 863 | 來源出版物: | Handbook of Single-Cell Technologies | 摘要: | Traditional analysis in cancer initiates an empirical screening on bulk tumors based on standard equipment. Nonetheless, the tumors inherently exhibit distinct characteristics, including heterogeneity/plasticity/morphology of cells, cell-matrix or cell-cell interactions, and in-depth mass transport. Such traditional analysis may not acquire the invaluable yield since the critical cells of interest are in the minority as well as their activities could be altered during preparation. In recent years, emerging techniques in single-cell analysis have opened a new avenue targeting precise cancer medicine, including single-cell genome/transcriptome, next-generation sequencing, tumor spheroid formation targeting cancer stem cells, and microfluidic approach for the physical assay of cell size (mass/volume/density), deformability, and electrokinetic properties from single cells. In this chapter, an overall view of current techniques and commercial equipment for single-cell analysis in cancer and their potential translation into clinic will be present. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/631756 | ISBN: | 9789811089534 | DOI: | 10.1007/978-981-10-8953-4_33 |
顯示於: | 生命科學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。