Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain
Journal
Human Vaccines and Immunotherapeutics
Journal Volume
17
Journal Issue
3
Pages
654
Date Issued
2021-01-01
Author(s)
Huang, Ping Han
Tsai, Hsiao Han
Liao, Bo Hung
Lin, Yi Ling
Jan, Jia Tsrong
Tao, Mi Hua
Chou, Yu Chi
Hu, Che Ming Jack
Abstract
A safe and effective vaccine candidate is urgently needed for the ongoing COVID-19 pandemic, caused by SARS-CoV-2. Here we report that recombinant SARS-CoV-2 RBD protein immunization in mice is able to elicit a strong antibody response and potent neutralizing capability as measured using live or pseudotyped SARS-CoV-2 neutralization assays.
Subjects
neutralizing antibodies; receptor-binding domain; SARS-CoV-2; vaccine
SDGs
Publisher
TAYLOR & FRANCIS INC
Type
other