Short-, Mid-, and Long-Term Associations Between PM2.5 and Stroke Incidence in Taiwan
Journal
Journal of occupational and environmental medicine
Journal Volume
63
Journal Issue
9
Pages
742
Date Issued
2021-09-01
Author(s)
Yang, Chun Pai
Li, Chung Yi
Huang, Winn Jung
Yang, Cheng Chia
Lu, Mei Chun
Lang, Hui Chu
Yan, Yuan Horng
Abstract
OBJECTIVE: To investigate the association between the risk of stroke and exposure to particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5) over various exposure periods. METHODS: This was a nationwide population-based case-control study in which 10,035 incident patients with a primary diagnosis of ischemic stroke each were matched with two randomly selected controls for sex, age, Charlson Comorbidity Index, year of stroke diagnosis, and level of urbanization. Multiple logistic models adjusted for potential confounders were used to assess the association of PM2.5 with ischemic stroke incidence. RESULTS: There were significant short-term, medium-term, and long-term relationships between PM2.5 exposure and ischemic stroke incidence. CONCLUSIONS: This study supports existing evidence that PM2.5 should be considered a risk factor for ischemic stroke.
Subjects
incidence; ischemic stroke; particulate matter; risk factor; Taiwan; PARTICULATE AIR-POLLUTION; ISCHEMIC-STROKE; MORTALITY; RISK; ATHEROSCLEROSIS; URBANIZATION; POLLUTANTS; EXPOSURE; DATABASE; DISEASE
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Type
journal article
