https://scholars.lib.ntu.edu.tw/handle/123456789/632604
標題: | A MICROFLUIDIC PLATFORM FOR UNDILUTED PLASMA SEPARATION AND ELECTROCHEMICAL DETECTION OF C-REACTIVE PROTEIN | 作者: | Lai, Zhi Xuan NIEN-TSU HUANG |
關鍵字: | Cardiovascular Disease | Electrochemical Detection | Microfluidics | Whole Blood Processing | 公開日期: | 1-一月-2021 | 來源出版物: | MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences | 摘要: | We develop a miniaturized microfluidic platform integrating membrane-based, sedimentation-assisted plasma separation with cardiovascular disease (CVD) biomarker detection. The microfluidic platform can extract 177 μL plasma from 400 µL whole blood within 7 minutes and subsequently detect the biomarker in the undiluted plasma by an embedded electrochemical impedance spectroscopy (EIS) sensor. The EIS sensor successfully detected C-reactive protein (CRP), a cardiovascular disease biomarker, in a broad range from 1 ng/mL to 10 µg/mL. Highly integrated, the microfluidic platform exhibits great potential for point-of-care (POC) diagnostics. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/632604 | ISBN: | 9781733419031 |
顯示於: | 電機工程學系 |
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