https://scholars.lib.ntu.edu.tw/handle/123456789/633479
標題: | The Effects of Bacillus licheniformis—Fermented Products on the Microbiota and Clinical Presentation of Cats with Chronic Diarrhea | 作者: | Lee, Ting Wei Chao, Tzu Yi HUI-WEN CHANG Cheng, Yeong Hsiang CHING-HO WU YEN-CHEN CHANG |
關鍵字: | Bacillus licheniformis-fermented products | chronic feline diarrhea | fecal microbiota | next-generation sequencing | probiotics | 公開日期: | 1-九月-2022 | 卷: | 12 | 期: | 17 | 來源出版物: | Animals | 摘要: | Bacillus licheniformis-fermented products (BLFP) are probiotics with antibacterial, antiviral, and anti-inflammatory properties that can improve growth performance. This study aimed to compare the fecal microbiota of diarrheal cats with chronic diarrhea (n = 8) with that of healthy cats (n = 4) from the same household using next-generation sequencing, and evaluate the effectiveness of oral administration of BLFP in relieving clinical signs and altering the intestinal microbiota in diarrheal cats. Six out of eight diarrheal cats showed clinical improvement after BLFP administration for 7 days, and the stool condition of the other two was normal. A higher Firmicutes/Bacteroidetes ratio was noted in the feces of diarrheal cats without clinical improvement as compared with those in the healthy cats and in the diarrheal cats with clinical improvement after receiving BLFP. The phylum Bacteroidetes and class Bacteroidia decreased significantly in diarrheal cats regardless of BLFP administration. Blautia spp., Ruminococcus torques, and Ruminococcus gnavus, which belong to the Clostridium cluster XIVa and have been reported as beneficial to intestinal health, increased significantly in feces after treatment. Furthermore, Clostridium perfringens also significantly decreased in diarrheal cats after BLFP administration. Overall, BLFP could be a potential probiotic to relieve gastrointestinal symptoms and improve fecal microbiota in cats with chronic diarrhea. |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85137844284&origin=resultslist&sort=plf-f https://scholars.lib.ntu.edu.tw/handle/123456789/633479 |
ISSN: | 2076-2615 | DOI: | 10.3390/ani12172187 |
顯示於: | 分子暨比較病理生物學研究所 |
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