https://scholars.lib.ntu.edu.tw/handle/123456789/634356
標題: | Characteristics and outcomes of full-thickness macular holes created during vitrectomy for proliferative diabetic retinopathy | 作者: | Tsui, Mei Chi CHUNG-MAY YANG Wang, Lu Chun |
關鍵字: | Diabetic vitrectomy | Fibrovascular proliferation | Full-thickness macular hole | Internal limiting membrane peeling | Inverted internal limiting membrane flap technique | Proliferative diabetic retinopathy | 公開日期: | 1-一月-2023 | 來源出版物: | International Ophthalmology | 摘要: | Purpose: To investigate the clinical features, management, and prognosis of full-thickness macular holes (FTMHs) inadvertently created during vitrectomy for eyes with proliferative diabetic retinopathy (PDR) and fibrovascular proliferation (FVP). Methods: Eyes with PDR and FVP that had intraoperatively created FTMHs were retrospectively collected as the study group, and age- and sex-matched subjects with PDR and FVP who did not have intraoperative FTMHs were selected as the control group. Fundus abnormalities, optical coherence tomography (OCT) features, and anatomical and functional outcomes were compared between the two groups. Results: Eleven eyes of 11 patients (5 male and 6 female) were identified as the study group. Follow-up duration was 36.8 ± 47.2 months. FTMHs were managed by ILM peeling or the inverted ILM flap technique. Anatomical success and MH closure were achieved in 100% of eyes in the study group. In comparison to the control group, the study group had a higher proportion of condensed prefoveal tissue (63.6% vs. 22.7%, p = 0.028), and a higher ratio of silicone oil tamponade (63.6% vs. 18.2%, p = 0.014), whereas there were no differences in preoperative and final BCVA, and the severity, activity, and locations of FVP between the two groups. Conclusion: Condensed prefoveal tissue was a risk factor of FTMHs created during operation for eyes with PDR and FVP. The ILM peeling or the inverted ILM flap technique may be beneficial for the treatment with favorable anatomical and functional outcomes. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/634356 | ISSN: | 01655701 | DOI: | 10.1007/s10792-023-02753-8 |
顯示於: | 醫學系 |
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