The effect of low-concentration atropine combined with auricular acupoint stimulation in myopia control
Journal
Complementary Therapies in Medicine
Journal Volume
22
Journal Issue
3
Date Issued
2014-01-01
Author(s)
Cheng, Han Chih
Abstract
Objectives: To compare the effect of myopia control between patients treated with low-concentration atropine eye drops combined with auricular acupoint stimulation and those treated with atropine alone. Design and settings: Single-blinded randomized controlled clinical trial in a regional teaching hospital. Interventions: The patients received either topical 0.125% atropine nightly plus auricular acupoint stimulation (0.125A. +. ACU group) or topical 0.125% atropine alone nightly (0.125A group). Main outcome measures: The changes in spherical equivalent (SE), axial length (AL), anterior chamber depth (ACD), and intraocular pressure (IOP) per year were compared between the two groups. Results: Seventy-three of 110 total patients (66.4%) completed at least 6 months of follow-up. Patients in the 0.125A. +. ACU group had less myopic progression and AL elongation (-0.41 diopter and 0.24. mm/year) than those in the 0.125A group (-0.66 diopter and 0.32. mm/year) (mean follow-up 14.7 months, p<. 0.0001 and p= 0.02, respectively). The ACD increased more in the 0.125A. +. ACU group than in the 0.125A group (0.076. mm vs. 0.023. mm/year, p= 0.0004). IOP decreased more in the 0.125A. +. ACU group than in the 0.125A group (-1.01. mmHg vs. -0.13. mmHg/year, p= 0.007). A decrease of 1. mmHg of IOP correlated with a decrease of myopic progression of 0.021 diopter/year (p= 0.006). Conclusions: Patients treated with 0.125% atropine eye drops plus auricular acupoint stimulation had less myopic progression, less axial length elongation, more anterior chamber deepening, and greater IOP reductions than those treated with 0.125% atropine alone. Auricular acupoint stimulation in combination with low-concentration topical atropine was beneficial for myopia control. © 2014 Elsevier Ltd.
Subjects
Acupuncture | Anterior chamber depth | Atropine | Auricular acupoint | Axial length | Intraocular pressure | Myopia
SDGs
Type
journal article