https://scholars.lib.ntu.edu.tw/handle/123456789/635003
標題: | Metformin Reduces Bone Resorption in Apical Periodontitis Through Regulation of Osteoblast and Osteoclast Differentiation | 作者: | Hong, Chi-Yuan SZE-KWAN LIN HAN-WEI WANG CHIA-TUNG SHUN Yang, Cheng-Ning EDDIE HSIANG HUA LAI SHIH-JUNG CHENG Chen, Mu-Hsiung Yang, Hsiang Lin, Hung-Ying Wu, Fang-Yu SANG-HENG KOK |
關鍵字: | Apical periodontitis; hypoxia; metformin; receptor activator of nuclear factor-κB ligand; runt-related transcription factor 2; tartrate-resistant acid phosphatase | 公開日期: | 16-七月-2023 | 來源出版物: | Journal of endodontics | 摘要: | We have previously demonstrated that auxiliary metformin therapy promotes healing of apical periodontitis. Here we aimed to investigate the effects of metformin on osteoblast differentiation and osteoclast formation in cultured cells and rat apical periodontitis. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/635003 | ISSN: | 00992399 | DOI: | 10.1016/j.joen.2023.07.005 |
顯示於: | 法醫學科所 |
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