https://scholars.lib.ntu.edu.tw/handle/123456789/635317
標題: | Inhibition of Viral Replication Reduces Transcriptionally Active Distinct Hepatitis B Virus Integrations With Implications on Host Gene Dysregulation | 作者: | Hsu, Yao-Chun Suri, Vithika Nguyen, Mindie H Huang, Yen-Tsung Chen, Chi-Yi Chang, I-Wei Tseng, Cheng-Hao Wu, Chun-Ying JAW-TOWN LIN Pan, David Z Gaggar, Anuj Podlaha, Ondrej |
關鍵字: | Antiviral Treatment; Chronic Hepatitis B; Hepatocellular Carcinogenesis; Transcriptome Analysis; Viral Integration | 公開日期: | 四月-2022 | 卷: | 162 | 期: | 4 | 起(迄)頁: | 1160 | 來源出版物: | Gastroenterology | 摘要: | Hepatocellular carcinogenesis of hepatitis B virus (HBV) infection may arise from integration of viral DNA into the host genome. We aimed to gauge the effect of viral inhibition on transcriptionally active HBV-host integration events and explore the correlation of viral integrations with host gene dysregulation. |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85125910391&doi=10.1053%2fj.gastro.2021.12.286&origin=inward&txGid=1424ac0195f2d6e7d40c0aafae79b415 https://scholars.lib.ntu.edu.tw/handle/123456789/635317 |
ISSN: | 00165085 | DOI: | 10.1053/j.gastro.2021.12.286 |
顯示於: | 醫學系 |
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