https://scholars.lib.ntu.edu.tw/handle/123456789/635390
標題: | A biocompatible needle-type glucose sensor based on platinum-electroplated carbon electrode | 作者: | Chen, Chien-Yuan Tamiya, E Ishihara, K Kosugi, Y Su, Y C Nakabayashi, N Karube, I |
關鍵字: | 2-methacryloyloxyethyl phosphorylcholine (MPC) | Biocompatibility | cellulose triacetate (CTA) | diffusion-limiting effect | glucose oxidase | glucose sensor | n-butylmethacrylate (BMA) | needle type | serum | 公開日期: | 九月-1992 | 卷: | 36 | 期: | 3 | 起(迄)頁: | 211 | 來源出版物: | Applied biochemistry and biotechnology | 摘要: | A biocompatible needle-type glucose sensor with a 3-electrode configuration was constructed. A platinum-electroplated carbon stick was used as the working electrode, Ag/AgCl as the reference electrode, and a disposable hypodermic needle made of stainless steel as the counter electrode. A Nafion membrane, an immobilized glucose oxidase (GOD) membrane, and a biocompatible membrane with diffusion-limiting effect were coated successively onto the working electrode. The sensor showed a rapid response (< 120 s in batch operation), good reproducibility (RE < 3%), good stability (over 36 h in control serum), a wide dynamic range (5-600 mg/dL glucose), and superior biocompatibility. It was used to determine glucose in serum. The data obtained from the sensor showed good agreement with that from a clinical autoanalyzer (R > 0.95). |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-0026922505&doi=10.1007%2fBF02921780&origin=inward&txGid=a224062bfe0b8a9282e289866e272fc2 https://scholars.lib.ntu.edu.tw/handle/123456789/635390 |
ISSN: | 0273-2289 | DOI: | 10.1007/BF02921780 |
顯示於: | 醫學系 |
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