https://scholars.lib.ntu.edu.tw/handle/123456789/635644
標題: | Bio-O-Pump: a novel portable microfluidic device driven by osmotic pressure | 作者: | Chuang, Chen Han YA-YU CHIANG |
關鍵字: | Energy free | Osmotic pressure | Passive pumping | Semipermeable biomimetic membrane | 公開日期: | 1-四月-2019 | 卷: | 284 | 來源出版物: | Sensors and Actuators, B: Chemical | 摘要: | The concepts of lab on a chip, miniaturised fluidic systems, and biochips entail the use of a fluid to perform analogue or digital operations. The temporal and spatial fluidic drive and control in microfluidic systems usually involves a complex pump, tubing, and connection system. Reducing the number of external components is crucial for use by scientists without an engineering background. In this paper, we present a novel pump-free device that uses an osmotic-pressure-driven flow to control and modulate fluid flow in microfluidic networks. The flow rate was regulated by controlling the osmotic area and the concentration of the draw solution, which comprised an easily accessible solution of electrolytes such as commercial sterile saline buffer and sodium chloride solution. The Bio-O-Pump can continuously generate liquid movement up to a flow rate of 4.88 mL h−1 over 1 h. This research also presents a single cell trapping application for biomedical uses. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/635644 | ISSN: | 09254005 | DOI: | 10.1016/j.snb.2019.01.020 |
顯示於: | 機械工程學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。