Proton Pump Inhibitor-unresponsive Laryngeal Symptoms Are Associated With Psychological Comorbidities and Sleep Disturbance: A Manometry and Impedance-pH Monitoring Study
Journal
Journal of neurogastroenterology and motility
Journal Volume
29
Journal Issue
3
Pages
314
Date Issued
2023-07-30
Author(s)
Abstract
Laryngeal symptoms are largely treated with empiric proton pump inhibitor (PPI) therapy if no apparent pathology shown on ear, nose, and throat evaluation and reflux-related etiologies are suspected. However, treatment response remains unsatisfactory. This study aimed to investigate the clinical and physiological characteristics of patients with PPI-refractory laryngeal symptoms.
Subjects
Gastroesophageal reflux; Larynx disease; Manometry; Psychological factors; Sleep disorder
SDGs
Type
journal article