https://scholars.lib.ntu.edu.tw/handle/123456789/637137
標題: | Biocompatible and antibacterial poly(lactic acid)/cellulose nanofiber‑silver nanoparticle biocomposites prepared via Pickering emulsion method | 作者: | Wu, Chun Nan Wang, Te En Hsieh, Chen Che KUAN-CHEN CHENG KEVIN CHIA-WEN WU |
關鍵字: | Antibacterial activity | Biocompatibility | Cellulose nanofiber | PLA | Silver nanoparticle | TEMPO | 公開日期: | 31-十二月-2023 | 卷: | 253 | 來源出版物: | International Journal of Biological Macromolecules | 摘要: | Developing biocompatible and antibacterial materials with biodegradable polymers is an ideal strategy to improve public health problems and plastic pollution simultaneously. In the present study, novel biocompatible and antibacterial poly (L-lactic acid) (PLLA, coded as P)/TEMPO-oxidized cellulose nanofiber (TOCNF, coded as T)‑silver nanoparticle (AgNP, coded as A) films were first developed. The core/shell PT Pickering emulsion was prepared by sonication treatment. The TOCNF shells with –COO−Na+ groups (∼1.5 mmol/g cellulose) were used as the support to in situ synthesize and immobilize AgNPs on the PT emulsion droplets. Silver nitrate (AgNO3) (1.5, 3.0, 4.5, and 6.0 mmol/g cellulose) was added to the PT emulsions. Then, ion-exchange reaction and hydrothermal reduction were conducted to form PTA (PTA1–PTA4) emulsions. After centrifugation to remove the excess Ag+, filtration, oven-drying, and hot-pressing, the PTA composite films were successfully prepared. The PTA3 film contained AgNPs 12.4 ± 2.8 nm in diameter and exhibited the highest antibacterial activities against the E. coli (85.2%) and S. aureus (80.1%) at 37 °C, where the initial bacterial suspension concentrations were approximately 2 × 108 CFU mL−1. Therefore, the biocompatible and antibacterial PTA3 film is a promising candidate for biomedical applications, in particular as an antibacterial bioactive packaging material. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/637137 | ISSN: | 01418130 | DOI: | 10.1016/j.ijbiomac.2023.127495 |
顯示於: | 化學工程學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。