DNA Methylation Biomarkers as Prediction Tools for Therapeutic Response and Prognosis in Intermediate-Stage Hepatocellular Carcinoma
Journal
Cancers
Journal Volume
15
Journal Issue
18
Date Issued
2023-09-07
Author(s)
Peng, Pey-Jey
Huang, Shao-Chang
Chuang, Meng-Rong
Su, Hung-Ju
Abstract
Alfa-fetoprotein (AFP), as the main serum tumor marker of hepatocellular carcinoma (HCC), is limited in terms of specificity and ability to predict outcomes. This study investigated the clinical utility of DNA methylation biomarkers to predict therapeutic responses and prognosis in intermediate-stage HCC.
Subjects
DNA methylation; hepatocellular carcinoma; locoregional therapy; tumor biomarker
Type
journal article