Neurotoxicity of a novel local anesthetic agent, ropivacaine: the possible roles of bursts of potential and cytoplasmic second messenger
Journal
Journal of the Formosan Medical Association = Taiwan yi zhi
Journal Volume
106
Journal Issue
10
Date Issued
2007-10
Author(s)
Abstract
Ropivacaine has been shown to induce convulsion following overdose or accidental intravenous injection, but the mechanisms are poorly understood. Using an identifiable central neuron from giant African snail, the authors studied the mechanism of ropivacaine-elicited bursts of potential and explored the possible mechanisms of ropivacaine-induced neurotoxicity.
Subjects
Central neuron | Convulsion | Ropivacaine | Second messenger | Snail
Type
journal article