https://scholars.lib.ntu.edu.tw/handle/123456789/637893
標題: | Effect of Obesity and Vitamin D Levels on Outcome Prediction in Critical Patients | 作者: | Wang, I. Ting Yang, Hsiu Wu Chang, Kuo Song Su, Yu Jang Chen, Chung Wei Yuan, Kuo Ching Wang, An Yi Wang, Yin Chin YIN-YI HAN Kuo, Li Kuo YU-CHANG YEH |
關鍵字: | critical care outcomes | critically ill | obesity | vitamin D | 公開日期: | 1-一月-2023 | 卷: | 17 | 期: | 4 | 來源出版物: | International Journal of Gerontology | 摘要: | Background: Vitamin D is an important nutrient for maintaining cardiovascular, endocrine, immune, and nervous system health. Body mass index (BMI) is one of the factors influencing vitamin D levels. We aimed to study the factors that play a role in the outcomes and prognoses of critically ill patients. Method: This study was conducted at four teaching hospitals in Northern Taiwan between August 2018 and July 2020. A total of 1421 critically ill patients admitted to the intensive care units (ICUs) were eligible for assessment. Patients were classified into two groups based on serum 25(OH)D levels: sufficiency (3 20 ng/ml) and insufficiency (< 20 ng/ml); and into four groups according to BMI: underweight (BMI < 18.5), normal weight (BMI 18.5–24.9), overweight (BMI 25–29.9), and obesity (BMI 3 30). Statistical analyses were performed, and a p-value < 0.05 indicated a significant difference. Results: More than half (57.9%) of the critically ill ICU patients had vitamin D deficiency (VDD); and VDD lengthened ICU stay by 2.5 days in vitamin D-deficit patients as compared to that in vitamin D-sufficient patients. Patients with obesity had a 4.2-day longer ICU stay (16.7 days) than that of the BMI < 30 group (12.5 days), which was significant (p = 0.009). They also had the lowest vitamin D levels (17.3 ng/mL) and the highest 90-day mortality rate (17.3%) compared to the other BMI groups. Conclusion: In caring for critical patients, physicians need to pay more attention to vitamin D levels and BMI factors, which may impact their outcome prediction. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/637893 | ISSN: | 18739598 | DOI: | 10.6890/IJGE.202310_17(4).0005 |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。