Accidentally Found Lung Cancer in Teenager Donor Lung
Journal
Thoracic Medicine
Journal Volume
38
Journal Issue
1
Pages
25
Date Issued
2023-03
Author(s)
Abstract
For most post-transplantation patients, the meantime from transplantation to the diagnosis of lung cancer was 76 months (range, 9-192 months). In previous, the cases were considered as induced lung cancer. Advances in immunosuppression management have led to prolonged survival in many transplant recipients. A by-product of this improvement, however, has been the identification of several complications of chronic immunosuppression. Among the most important of these is the substantially increased incidence of malignancies in transplant recipients. But in our recipient, a left upper lung adenocarcinoma was accidentally found, which is 0.001 cubic centimeter in size, and resected randomly due to the oversize of the lung during the sternum closure. In past, most post-transplantation lung cancer is considered immunosuppression related. But our case showed the incidence might be underestimated, especially in the high lung cancer prevalence area like Taiwan. The combination of the donor's family history and the routine pre-transplantation donor’s chest CT might be help for early detection of donor's lung malignancy. The frozen pathology could be applied after the pre-donation lung computed tomography scan if suspected lesion was identified. In this way, we believe the pre-donation evaluation could be more adequate.
Subjects
lung cancer
adenocarcinoma
teenager donor lung
teenager recipient
lung transplantation
Publisher
台灣胸腔暨重症加護醫學會
Type
journal article