Exploring the human gut microbiota targets in relation to the use of contemporary antidepressants
Journal
Journal of affective disorders
Journal Volume
344
Pages
473
Date Issued
2024-01-01
Author(s)
Lin, Shih-Kai Kevin
Chen, Chun-Hsin
Lu, Mong-Liang
Hsu, Cheng-Dien
Chiu, Yi-Hang
Chen, Hui-Mei
Chung, Yu-Chu Ella
Abstract
Antidepressants, specifically selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), are commonly prescribed for depression treatment. Animal studies have shown that antidepressants can influence gut microbiota composition and specific bacterial taxa. We aimed to investigate the association between antidepressant use and human gut microbiota composition and functional pathway.
Subjects
Antidepressants; Depression; Gut microbiome; Selective serotonin reuptake inhibitors; Serotonin-norepinephrine reuptake inhibitors
SDGs
Type
journal article