https://scholars.lib.ntu.edu.tw/handle/123456789/639364
標題: | Minimally invasive endoscopic evacuation with the novel, portable Axonpen neuroendoscopic system for spontaneous intracerebral hemorrhage | 作者: | Lee, Cheng-Chi ABEL PO-HAO HUANG Chen, Ching-Chang Liu, Zhuo-Hao Yeap, Mun-Chun Chen, Ko-Ting Hsu, Peng-Wei Wei, Kuo-Chen Chen, Chun-Ting Wang, Yu-Chi Chang, Ting-Wei Chuang, Chi-Cheng |
關鍵字: | Endoscopic hematoma evacuation; Minimally invasive surgery; Spontaneous intracerebral hemorrhage | 公開日期: | 一月-2024 | 卷: | 119 | 來源出版物: | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia | 摘要: | Minimally invasive surgeries have shown potential to improve mortality and clinical outcomes of spontaneous intracerebral hemorrhage (ICH). The present study assessed the first-in-human outcomes of a novel, portable neuroendoscopic system for ICH evacuation at our single center. This neuroendoscopic system integrates real-time visualization into a handpiece which has controllable suction, irrigation, and coagulation to allow a neurosurgeon to conduct minimally invasive ICH evacuation independently with bimanual dexterity. Pre- and postoperative data of ten patients who had spontaneous basal ganglia hemorrhage (mean: 46.5 ± 12.2 mL) and underwent evacuation with the specified neuroendoscopic system were collected prospectively. The mean time to receive surgery was 12.1 ± 7.6 h. Mean operative time was 3.4 ± 0.9 h. The mean hematoma volume decreased to 6.0 ± 3.9 mL at postoperative 6 h, resulting in a mean volume reduction of 86.0 ± 11.2% (P = 0.005). The median length of intensive care unit stay was 3 days (IQR, 3-4 days). At discharge, the median Glasgow Coma Scale (GCS) score significantly improved to 11.5 (IQR, 11-15; P = 0.016), and the median modified Rankin Scale (mRS) score was 4 (IQR, 4-5). Six patients (60%) showed a favorable mRS score of ≤ 3 on their last return visit. Neither death nor rebleeding occurred during the follow-up periods. Integrated design of the innovative device is valuable to optimize minimally invasive endoscopic ICH evacuation procedure. Further studies are needed to clarify long-term benefits from such type of the innovative device to early intervention of ICH. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639364 | ISSN: | 09675868 | DOI: | 10.1016/j.jocn.2023.11.003 |
顯示於: | 醫學系 |
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