https://scholars.lib.ntu.edu.tw/handle/123456789/639830
標題: | C-C chemokine receptor 4 (CCR4)-positive regulatory T cells interact with tumor-associated macrophages to facilitate metastatic potential after radiation | 作者: | YUN CHIANG Lu, Li-Feng Tsai, Chao-Ling Tsai, Yu-Chieh Wang, Chung-Chieh FU-JEN HSUEH CHAO-YUAN HUANG CHUNG-HSIN CHEN YEONG-SHIAU PU CHIA-HSIEN CHENG |
關鍵字: | CCR4; Radiotherapy; Regulatory T cells; Tumor microenvironment; Tumor-associated macrophage | 公開日期: | 二月-2024 | 卷: | 198 | 來源出版物: | European journal of cancer (Oxford, England : 1990) | 摘要: | Our previous study revealed that elevated C-C motif chemokine ligand 2 (CCL2) secretion by irradiated cancer cells recruited C-C motif chemokine receptor 2 (CCR2)-positive myeloid cells and polarized M2-type tumor-associated macrophages (TAMs), promoting lung metastasis in an established mouse model. This study investigated the impact of CCL2 and TAMs on adaptive immunity. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639830 | ISSN: | 09598049 | DOI: | 10.1016/j.ejca.2023.113521 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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