Reversal of arterial stiffness in medically and surgically treated unilateral primary aldosteronism
Journal
Journal of hypertension
Journal Volume
42
Journal Issue
3
Pages
538–545
Date Issued
2024-03-01
Author(s)
Chang, Yi-Yao
Chiu, Yu-Wei
Huang, Wei-Chieh
Abstract
Hyperaldosteronism has adverse effects on cardiovascular structure and function. Laparoscopic adrenalectomy is the gold standard for patients with unilateral primary aldosteronism. For unilateral primary aldosteronism patients unable or unwilling to undergo surgery, the effects of mineralocorticoid receptor antagonists (MRAs) on the reversibility of arterial stiffness and other clinical data remain unclear. We aimed to compare the reversibility of arterial stiffness using pulse wave velocity (PWV) and other clinical parameters between surgically and medically treated unilateral primary aldosteronism patients.
Subjects
adrenalectomy | aldosterone-producing adenoma | arterial stiffness | mineralocorticoid receptor antagonist | primary aldosteronism | pulse wave velocity | Taiwan Primary Aldosteronism Investigation
Type
journal article