https://scholars.lib.ntu.edu.tw/handle/123456789/640721
標題: | TEM1/endosialin/CD248 promotes pathologic scarring and TGF-β activity through its receptor stability in dermal fibroblasts | 作者: | Hong, Yi-Kai Lin, Yu-Chen Cheng, Tsung-Lin Lai, Chao-Han Chang, Yi-Han Huang, Yu-Lun Hung, Chia-Yi Wu, Chen-Han Hung, Kuo-Shu Ku, Ya-Chu Ho, Yen-Ting Tang, Ming-Jer SHU-WHA LIN Shi, Guey-Yueh McGrath, John A Wu, Hua-Lin Hsu, Chao-Kai |
關鍵字: | Fibroblast activation; Hypertrophic scar; Keloid; TEM1/endosialin/CD248; TGF-β | 公開日期: | 23-一月-2024 | 卷: | 31 | 期: | 1 | 來源出版物: | Journal of biomedical science | 摘要: | Pathologic scars, including keloids and hypertrophic scars, represent a common form of exaggerated cutaneous scarring that is difficult to prevent or treat effectively. Additionally, the pathobiology of pathologic scars remains poorly understood. We aim at investigating the impact of TEM1 (also known as endosialin or CD248), which is a glycosylated type I transmembrane protein, on development of pathologic scars. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/640721 | ISSN: | 10217770 | DOI: | 10.1186/s12929-024-01001-0 |
顯示於: | 醫學檢驗暨生物技術學系 |
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