https://scholars.lib.ntu.edu.tw/handle/123456789/641124
標題: | Asia-Pacific consensus on long-term and sequential therapy for osteoporosis | 作者: | Tai, Ta-Wei HSUAN-YU CHEN Shih, Chien-An Huang, Chun-Feng McCloskey, Eugene Lee, Joon-Kiong Yeap, Swan Sim Cheung, Ching-Lung Charatcharoenwitthaya, Natthinee Jaisamrarn, Unnop Kuptniratsaikul, Vilai RONG-SEN YANG Lin, Sung-Yen Taguchi, Akira Mori, Satoshi Li-Yu, Julie Ang, Seng Bin Chan, Ding-Cheng Chan, Wai Sin Ng, Hou Chen, Jung-Fu Tu, Shih-Te Chuang, Hai-Hua Chang, Yin-Fan Chen, Fang-Ping Tsai, Keh-Sung Ebeling, Peter R. Nistal Rodríguez, Francisco Javier Shi, Huipeng Hwang, Kyu Ri Kim, Kwang-Kyoun Chung, Yoon-Sok Reid, Ian R. Chandran, Manju Ferrari, Serge Hew, Fen Lee Ho-Pham, Lan T. Nguyen, Tuan Van Nguyen, Van Hy Lekamwasam, Sarath Pandey, Dipendra Bhadada, Sanjay Chen, Chung-Hwan Hwang, Jawl-Shan Wu, Chih-Hsing |
關鍵字: | Sequential therapy;Anti-osteoporosis medication;Fracture prevention;Consensus | 公開日期: | 2024 | 來源出版物: | Osteoporosis and Sarcopenia | 摘要: | Objectives This study aimed to present the Asia-Pacific consensus on long-term and sequential therapy for osteoporosis, offering evidence-based recommendations for the effective management of this chronic condition. The primary focus is on achieving optimal fracture prevention through a comprehensive, individualized approach. Methods A panel of experts convened to develop consensus statements by synthesizing the current literature and leveraging clinical expertise. The review encompassed long-term anti-osteoporosis medication goals, first-line treatments for individuals at very high fracture risk, and the strategic integration of anabolic and antiresorptive agents in sequential therapy approaches. Results The panelists reached a consensus on 12 statements. Key recommendations included advocating for anabolic agents as the first-line treatment for individuals at very high fracture risk and transitioning to antiresorptive agents following the completion of anabolic therapy. Anabolic therapy remains an option for individuals experiencing new fractures or persistent high fracture risk despite antiresorptive treatment. In cases of inadequate response, the consensus recommended considering a switch to more potent medications. The consensus also addressed the management of medication-related complications, proposing alternatives instead of discontinuation of treatment. Conclusions This consensus provides a comprehensive, cost-effective strategy for fracture prevention with an emphasis on shared decision-making and the incorporation of country-specific case management systems, such as fracture liaison services. It serves as a valuable guide for healthcare professionals in the Asia-Pacific region, contributing to the ongoing evolution of osteoporosis management. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641124 | ISSN: | 24055255 | DOI: | 10.1016/j.afos.2024.02.001 |
顯示於: | 醫學院附設醫院 (臺大醫院) |
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