https://scholars.lib.ntu.edu.tw/handle/123456789/641201
標題: | Evaluating clinical efficacy of hospital-based surveillance with mammography and ultrasonography for breast cancer | 作者: | Han, Hsin-Ju Huang, Ching-Shui TZU-PIN LU Tseng, Ling-Ming Chie, Wei-Chu Huang, Chi-Cheng |
關鍵字: | Breast cancer; Hospital cohort; Mammography; Sonography; Surveillance | 公開日期: | 一月-2024 | 出版社: | Elsevier B.V. | 卷: | 123 | 期: | 1 | 起(迄)頁: | 78-87 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Periodic mammography and/or sonography examinations are conducted across numerous hospitals nationalwidely, especially for antedees with a positive mammography screening. Despite the regular practice, clinical efficacy of hospital-based breast cancer surveillance remains unclear. Specifically, the impact of surveillance interval upon survival and prognostic surrogates stratified by menopausal status, as well as malignant transition rate should be deciphered. We retrieved cancer registry to ascertain 841 breast cancers with surveillance history through administration data. Healthy controls underwent breast surveillance and were concurrently free of cancer. More benign diseases rather than cancers were identified from premenopausal women (age ≤50 years) with sonography alone within one year, as well as older women (age >50) with both mammography and sonography one to two years before a cancer or benign diagnosis. Among breast cancers, mammography alone during the antecedent one to two years had a protective effect for diagnosing carcinoma in situ rather than invasive cancer (age-adjusted odds ratio: 0.048, P = 0.016). Three-state time homogeneous Markov model showed that hospital-based breast surveillance within 2 years of disease onset reduced the malignant transition rate by 65.16% (59.79-76.74%). The clinical efficacy of breast cancer surveillance was evidenced. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641201 | ISSN: | 0929-6646 | DOI: | 10.1016/j.jfma.2023.06.006 |
顯示於: | 健康數據拓析統計研究所 |
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