Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study
Journal
Lancet
Journal Volume
403
Journal Issue
10421
Pages
55-66
Date Issued
2024-01-06
Author(s)
Dharmayat, Kanika Inamdar
Vallejo-Vaz, Antonio J.
Stevens, Christophe A.T.
Brandts, Julia M.
Lyons, Alexander R.M.
Groselj, Urh
Abifadel, Marianne
Aguilar-Salinas, Carlos A.
Alhabib, Khalid
Alkhnifsawi, Mutaz
Almahmeed, Wael
Alnouri, Fahad
Alonso, Rodrigo
Al-Rasadi, Khalid
Ashavaid, Tester F.
Banach, Maciej
Béliard, Sophie
Binder, Christoph
Bourbon, Mafalda
Chlebus, Krzysztof
Corral, Pablo
Cruz, Diogo
Descamps, Olivier S.
Drogari, Euridiki
Durst, Ronen
Ezhov, Marat V.
Genest, Jacques
Harada-Shiba, Mariko
Holven, Kirsten B.
Humphries, Steve E.
Khovidhunkit, Weerapan
Lalic, Katarina
Laufs, Ulrich
Liberopoulos, Evangelos
Roeters van Lennep, Jeanine
Lima-Martinez, Marcos Miguel
Lin, Jie
Maher, Vincent
März, Winfried
Miserez, André R.
Mitchenko, Olena
Nawawi, Hapizah
Panayiotou, Andrie G.
Paragh, György
Postadzhiyan, Arman
Reda, Ashraf
Reiner, Željko
Reyes, Ximena
Sadiq, Fouzia
Sahebkar, Amirhossein
Schunkert, Heribert
Shek, Aleksandr B.
Stroes, Eric
Subramaniam, Tavintharan
Susekov, Andrey
Vázquez Cárdenas, Alejandra
Huong Truong, Thanh
Tselepis, Alexandros D.
Vohnout, Branislav
Wang, Luya
Yamashita, Shizuya
Al-Sarraf, Ahmad
Al-Sayed, Nasreen
Davletov, Kairat
Dwiputra, Bambang
Gaita, Dan
Kayikcioglu, Meral
Latkovskis, Gustavs
Marais, A. David
Thushara Matthias, Anne
Mirrakhimov, Erkin
Nordestgaard, Børge G.
Petrulioniene, Zaneta
Pojskic, Belma
Sadoh, Wilson
Tilney, Myra
Tomlinson, Brian
Tybjærg-Hansen, Anne
Viigimaa, Margus
Catapano, Alberico L.
Freiberger, Tomas
Hovingh, G. Kees
Mata, Pedro
Soran, Handrean
Raal, Frederick
Watts, Gerald F.
Schreier, Laura
Bañares, Virginia
Greber-Platzer, Susanne
Baumgartner-Kaut, Margot
de Gier, Charlotte
Dieplinger, Hans
Höllerl, Florian
Innerhofer, Reinhold
Karall, Daniela
Lischka, Julia
Ludvik, Bernhard
Mäser, Martin
Scholl-Bürgi, Sabine
Abstract
Approximately 450 000 children are born with familial hypercholesterolaemia worldwide every year, yet only 2·1% of adults with familial hypercholesterolaemia were diagnosed before age 18 years via current diagnostic approaches, which are derived from observations in adults. We aimed to characterise children and adolescents with heterozygous familial hypercholesterolaemia (HeFH) and understand current approaches to the identification and management of familial hypercholesterolaemia to inform future public health strategies.
Publisher
Elsevier B.V.
Type
journal article