https://scholars.lib.ntu.edu.tw/handle/123456789/641515
標題: | Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C | 作者: | Fakih, Marwan G Salvatore, Lisa Esaki, Taito Modest, Dominik P Lopez-Bravo, David P Taieb, Julien Karamouzis, Michalis V Ruiz-Garcia, Erika Kim, Tae-Won Kuboki, Yasutoshi Meriggi, Fausto Cunningham, David KUN-HUEI YEH Chan, Emily Chao, Joseph Saportas, Yaneth Tran, Qui Cremolini, Chiara Pietrantonio, Filippo |
公開日期: | 7-十二月-2023 | 卷: | 389 | 期: | 23 | 來源出版物: | The New England journal of medicine | 摘要: | KRAS G12C is a mutation that occurs in approximately 3 to 4% of patients with metastatic colorectal cancer. Monotherapy with KRAS G12C inhibitors has yielded only modest efficacy. Combining the KRAS G12C inhibitor sotorasib with panitumumab, an epidermal growth factor receptor (EGFR) inhibitor, may be an effective strategy. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641515 | ISSN: | 00284793 | DOI: | 10.1056/NEJMoa2308795 |
顯示於: | 腫瘤醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。