https://scholars.lib.ntu.edu.tw/handle/123456789/641649
標題: | Risk of Non-melanoma Skin Cancer in Patients with Chronic Kidney Disease and its Relationship to Uraemic Pruritus | 作者: | Wang, Chia-Chen Tang, Chao-Hsiun Huang, Siao-Yuan KUAN-CHIH HUANG Sue, Yuh-Mou |
關鍵字: | Chronic kidney disease | Epidemiology | Non-melanoma skin cancer | Uraemic pruritus | 公開日期: | 15-十一月-2017 | 卷: | 97 | 期: | 10 | 起(迄)頁: | 1230 | 來源出版物: | Acta dermato-venereologica | 摘要: | This study investigated the risk of non-melanoma skin cancer (NMSC) in pre-dialysis patients with chronic kidney disease (CKD) and explored associated risk factors. A population-based cohort of 1,515,858 Taiwanese CKD patients was included. The standardized incidence ratio (SIR) for incident NMSC was determined. Compared with the general population, a 1.14-fold risk of NMSC was found in the CKD cohort. NMSC risk was significant in patients with pre-dialysis stage 5 CKD and anaemia (1.48-fold), and in those with uraemic pruritus after long-term antihistamine treatment (1.38-fold). A higher SIR for NMSC was found in younger patients with CKD (age < 70 years, 1.34-fold; age 20-39 years, 1.63-fold), stage 5 CKD with anaemia (age < 70 years, 2.09-fold), and uraemic pruritus (age <70 years, 2.22-fold). Pre-dialysis patients with CKD are at higher risk of NMSC, especially those with advanced-stage CKD, and those with uraemic pruritus. |
URI: | https://www.scopus.com/record/display.uri?eid=2-s2.0-85032655703&doi=10.2340%2f00015555-2762&origin=inward&txGid=d242f636c02e436fbd750f3014edc05f https://scholars.lib.ntu.edu.tw/handle/123456789/641649 |
ISSN: | 00015555 | DOI: | 10.2340/00015555-2762 |
顯示於: | 醫學系 |
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