https://scholars.lib.ntu.edu.tw/handle/123456789/641753
標題: | Highly catalytic Prussian blue analogues and their application on the three-dimensional origami paper-based sweat sensors | 作者: | Chen, Wei-Ting Yan, Chi Fong Yu, Cheng Ju YING-CHIH LIAO CHIEN-FU CHEN |
關鍵字: | Lactate | One-pot synthesis | Paper-based electrochemical sensor | Prussian blue analogues | Sweat sensor | 公開日期: | 15-六月-2024 | 卷: | 254 | 來源出版物: | Biosensors and Bioelectronics | 摘要: | Prussian blue analogues (PBAs) are promising materials due to their rich active sites and straightforward synthesis. However, their limited conductivity and electron transfer inefficiency hinder practical applications. This study utilizes a simple one-pot synthesis approach to produce a tungsten-disulfide (WS2) and iron-cobalt Prussian blue analogue composite (WS2-PBA), enhancing conductivity and electron transfer rate performance. Through the inclusion of sodium citrate into the solution, the S-edge site concentration of WS2 increases. This augmentation introduces additional active sites and defects into the catalyst, enhancing its catalytic activity. The effectiveness of the WS2-PBA 3D-Origami paper device for lactate detection in sweat is also evaluated for biomedical applications. The device demonstrated a robust relationship between the lactate concentration and current intensity (R2 = 0.997), with a detection limit of 1.83 mM. Additionally, this platform has successfully detected lactate in clinical sweat, correlating with the high-performance liquid chromatography test results, suggesting promising prospects for clinical diagnosis. In the future, the excellent catalytic and Rct performance of the WS2-PBA will enable its use in biomedical applications. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/641753 | ISSN: | 09565663 | DOI: | 10.1016/j.bios.2024.116188 |
顯示於: | 化學工程學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。