Soft probe scanning electrochemical microscopy with spider array for visualizing biomarkers and redox active proteins in animal tissues
Journal
ECS Transactions
Journal Volume
77
Journal Issue
7
Start Page
85
End Page
90
ISSN
19386737
ISBN (of the container)
9781607688105
Date Issued
2017
Author(s)
Abstract
We present soft spider array for gentle contact mode scanning electrochemical microscopy (SECM) imaging of tissues. The spider array contains up to eight completely individual, parallel, and flexible carbon microelectrodes designed to scan square centimeter sized areas on reasonable time scales while avoiding sample aging and electrode fouling. The contact mode enables the scanning of largely curved samples at a constant distance. The spider array is applied for the SECM imaging of the distribution of certain biomarkers, such as tyrosinase, in thin tumor tissues as well as thick tumor blocks. Furthermore, the spider array can be applied for mapping the antioxidant distribution in an apple peel. © The Electrochemical Society.
Event(s)
Symposium on Solid-State Electronics and Photonics in Biology and Medicine 4 - 231st ECS Meeting 2017, 28 May 2017 through 1 June 2017, New Orleans. Code: 128191
Publisher
Electrochemical Society Inc.
Type
conference paper