Endotracheal enucleation and para-toluenesulfonamide injection for adenoid cystic carcinoma in the upper trachea: A novel therapeutic approach.
Journal
Thoracic cancer
Journal Volume
15
Journal Issue
16
ISSN
1759-7714
Date Issued
2024-06
Author(s)
Lu, Hsiao-Hung
Abstract
We present a case of an adenoid cystic carcinoma (ACC) located in the upper trachea, which resulted in significant airway blockage, that was unsuitable for surgical removal due to concerns about functional impairment. Instead, endotracheal enucleation via rigid bronchoscopy was performed initially, followed by the injection of a novel tumor ablation agent known as para-toluenesulfonamide (PTS). We detail the dosing regimen, effectiveness evaluation, and post-treatment follow-up. The study highlights the potential of PTS injection as a viable alternative treatment option for patients with ACC who cannot undergo surgical resection and feasibility of lipiodol to monitor treatment effect. This research adds to the existing knowledge on ACC treatment and provides new therapeutic possibilities for patients with tracheal ACC.
Subjects
ablation techniques
adenoid cystic carcinoma
airway obstruction
non‐small‐cell lung cancer
para‐toluenesulfonamide
SDGs
Publisher
John Wiley and Sons Inc
Type
journal article