Carbohydrate Polymers, Polymeric Nano Drugs, and Nanoparticles Are Used for Advanced Drug Delivery and Therapeutics in Ocular Diseases
Journal
Polymers for Advanced Technologies
Journal Volume
36
Journal Issue
2
Start Page
e70094
ISSN
1042-7147
1099-1581
Date Issued
2025-02
Author(s)
Abstract
Nanotechnology has recently attracted research attention, given its wide applications in biomedicine. Novel nontoxic nano drugs functionalized with carbohydrate polymers are widely used in in vivo bioresearch, but their application to the ocular system remains challenging. Nanostructured materials and nanoparticles functionalized with carbohydrate polymers and other biological macromolecules are clinically used as nano eye drops, incorporated into therapeutic contact lenses, and used as nano wafers and nanofibers. Moreover, they can be used as drug delivery, therapeutic, and bioimaging systems for eye diseases. In this review, nano ophthalmology therapeutic and drug delivery systems based on nanostructured materials and nanoparticles conjugated with carbohydrate polymers were investigated. Meanwhile, increasing the effect of the nano-drug mucoadhesion by using the polymer complexes and polysaccharides is discussed. The design of pioneering nanomaterials has enabled the development of effective therapies in ophthalmology.
Subjects
carbohydrate polymers
drug delivery
nanoparticles
ocular system
polymeric nanotherapeutic agents
SDGs
Publisher
Wiley
Type
journal article