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.National Taiwan University / 國立臺灣大學
Project / 研究計畫
Arnt Expression in the Pathogenesis of Myelodysplastic Syndrome and Its Clinical Implication (III)=ARNT基因表現在骨髓化生不良症候群的致病機轉及其臨床角色(3/3)
Arnt Expression in the Pathogenesis of Myelodysplastic Syndrome and Its Clinical Implication (III)=ARNT基因表現在骨髓化生不良症候群的致病機轉及其臨床角色(3/3)
Details
Primary Data
Project title
ARNT基因表現在骨髓化生不良症候群的致病機轉及其臨床角色(3/3)
Internal ID
NSTC113-2314-B002-010
Principal Investigator
HSIN-AN HOU
Start Date
August 1, 2024
End Date
July 31, 2025
Investigators
LIANG-IN LIN
莊淳宇
Organizations
Internal Medicine
Partner Organizations
National Science and Technology Council
Description
Keywords
myelodysplastic syndrome (MDS)
environmental chemical exposure
ARNT gene
genetic alterations
prognosis
pathogenesis mechanism
Description
這項研究的成果將有助於了解 ARNT表現在骨髓化生不良症候群的發生及進展中扮演的角色及ARNT 表現與炎性體物質或其他基因變異的關連及其臨床重要性。轉殖基因斑馬魚活體模式將有助於瞭解 ARNT 基因在造血功能細胞的作用及骨髓化生不良症候群癌化過程的病生理角色,也將有助於制定有效的治療方法,做為個人化醫療重要的基石。
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