Cell-Cell Communication Through Deformation of Extracellular Matrix
Journal
2024 IEEE 6th Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability (ECBIOS)
Part Of
2024 IEEE 6th Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability (ECBIOS)
Start Page
25
End Page
28
Date Issued
2024-06-14
Author(s)
Abstract
Understanding cell-cell communication in cancer is important because cancer cells communicate to facilitate collective migration, such as during cancer progression and metastasis. We investigated how cancer cells communicate to facilitate their collective motion. We considered two major modes of cell-cell communication: chemical and mechanical. The results showed that chemical communication through specific signal molecules investigated in this study is not the only communication mechanism. Additionally, an aggregate of cells deforms their surrounding ECM, enabling mechanical communication.
Event(s)
2024, 6th IEEE Eurasia Conference on Biomedical Engineering, Healthcare and Sustainability, ECBIOS 2024, Tainan, 14 June 2024 through 16 June 2024. Code 207154
Subjects
cell-cell communication
collective migration
extracellular matrix
mechanical communication
SDGs
Publisher
IEEE
Type
conference paper