Enhancing Microwave Ablation for Lung Lesions with Cone-Beam Computed Tomography Guidance and Intrapulmonary Fine Adjustment in a Hybrid Operating Room.
Journal
Academic radiology
Journal Volume
32
Journal Issue
12
Start Page
7591
End Page
7600
ISSN
1878-4046
Date Issued
2025-07-18
Author(s)
Su, Po-Keng
Malwade, Shwetambara
Chung, Wen-Yuan
Chen, Shu-Chun
Abstract
Rationale and Objectives: To review outcomes of the first 150 consecutive microwave ablation (MWA) cases at our institution to assess the safety and diagnostic performance of a new workflow for cone-beam computed tomography (CBCT)-guided percutaneous MWA performed under general anesthesia in a hybrid operating room (HOR). Materials and Methods: This retrospective study included 150 consecutive patients who underwent MWA in the CBCT-equipped HOR between July 2020 and January 2024. The procedural workflow involved general anesthesia with patient fixation, CBCT scanning, iGuide needle pathway planning, needle placement with a laser beam and augmented fluoroscopy guidance, and post-procedure ablation-zone assessment. Technical advancements included the use of a coaxial needle for synchronous biopsy and ablation and a fine adjustment tool. Results: In total, 145 lesions in 127 patients (82 women and 45 men; mean age, 59.8 ± 13.1 years [standard deviation]; single nodule, 113 patients; multiple nodules, 14 patients) were analyzed. The median global operating-room time, procedure time, total dose area product, and postoperative stay were 110 min, 45 min, 19,701 μGym², and 2 days, respectively. CBCT-guided MWA improved diagnostic yield for subcentimeter lung lesions to 50.0% with intra-parenchymal fine adjustment, compared to 10.1% without. Pneumothorax rates decreased significantly to 6% with coaxial needles for biopsy and ablation, compared to 12.1% with prior methods. Post-procedure complications were mostly tolerable, with two fatal complications occurring in the early cohort. Conclusion: The MWA technique is safe and feasible, with various technical strategies enhancing its efficacy. The intra-parenchymal fine adjustment method significantly improves small-nodule biopsy yield.
Subjects
Ablation techniques
Anesthesia, general
Cone-beam computed tomography
Lung neoplasms
Microwaves
Type
journal article