https://scholars.lib.ntu.edu.tw/handle/123456789/543923
標題: | Neurotrophic keratitis in autoimmune polyglandular syndrome type 1: a case report | 作者: | Wu, Po-Ying Chang, Huai-Wen WEI-LI CHEN |
關鍵字: | Autoimmune polyglandular syndrome type 1 (APS-1); Case report; In vivo confocal microscopy; Neurotrophic keratitis | 公開日期: | 7-一月-2021 | 卷: | 21 | 期: | 1 | 來源出版物: | BMC ophthalmology | 摘要: | Autoimmune polyglandular syndrome type 1 (APS-1) is a rare autosomal recessive disease. In patients with APS-1, the most frequently reported ocular manifestations are keratoconjunctivitis with dry eye and retinal degeneration. However, to our knowledge, no research studies have reported the relationship between APS-1 and neurotrophic keratitis (NK). Possible explanations such as limbus cell deficiency being the primary cause of APS-1 keratopathy are not applicable to our unusual case of the patient with APS-1 presenting as ocular surface disease with NK. Our case findings suggest a new explanation for the observed corneal pathology and a potential treatment for these patients. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/543923 | ISSN: | 1471-2415 | DOI: | 10.1186/s12886-020-01770-w | SDG/關鍵字: | adult; case report; complication; cornea; dry eye; female; hereditary corneal dystrophy; human; keratitis; polyendocrinopathy; Adult; Cornea; Corneal Dystrophies, Hereditary; Dry Eye Syndromes; Female; Humans; Keratitis; Polyendocrinopathies, Autoimmune |
顯示於: | 醫學系 |
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