https://scholars.lib.ntu.edu.tw/handle/123456789/581245
Title: | Detection of electrically neutral and nonpolar molecules in ionic solutions using silicon nanowires | Authors: | Wu Y.-P Chu C.-J Tsai L.-C Su Y.-W Chen P.-H Moodley M.K Huang D Chen Y.-T Yang Y.-J YIT-TSONG CHEN YING-JAY YANG |
Keywords: | Amino acids; Molecular interactions; Molecular structure; Nanosensors; Nanowires; Negative ions; Permittivity; Complex impedance; Fundamental characteristics; Molecular charge; Nanowire sensors; Neutral molecules; Nonpolar molecules; Permittivity change; Silicon nanowires; Molecules | Issue Date: | 2017 | Journal Volume: | 28 | Journal Issue: | 16 | Source: | Nanotechnology | Abstract: | We report on a technique that can extend the use of nanowire sensors to the detection of interactions involving nonpolar and neutral molecules in an ionic solution environment. This technique makes use of the fact that molecular interactions result in a change in the permittivity of the molecules involved. For the interactions taking place at the surface of nanowires, this permittivity change can be determined from the analysis of the measured complex impedance of the nanowire. To demonstrate this technique, histidine was detected using different charge polarities controlled by the pH value of the solution. This included the detection of electrically neutral histidine at a sensitivity of 1 pM. Furthermore, it is shown that nonpolar molecules, such as hexane, can also be detected. The technique is applicable to the use of nanowires with and without a surface-insulating oxide. We show that information about the changes in amplitude and the phase of the complex impedance reveals the fundamental characteristics of the molecular interactions, including the molecular field and the permittivity. ? 2017 IOP Publishing Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85016146803&doi=10.1088%2f1361-6528%2faa63a6&partnerID=40&md5=9331ac76c979ddeb8382c3b0b3ef7516 https://scholars.lib.ntu.edu.tw/handle/123456789/581245 |
ISSN: | 09574484 | DOI: | 10.1088/1361-6528/aa63a6 |
Appears in Collections: | 電機工程學系 |
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