公開日期 | 標題 | 作者 | 來源出版物 | scopus | WOS | 全文 |
2024 | A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer | Ye, Pei-Chen; Leu, Wohn-Jenn; Yeh, Tsung-Yu; Hsu, Yu-Tung; Lin, Yi-Chin; Wei, Zi-Yuan; Chen, Yi-Chin; Chiang, Yi-Chang; Hsu, Jui-Ling; Chan, She-Hung; LIH-CHING HSU ; JI-WANG CHERN ; CHAO-WU YU ; JIH-HWA GUH | The Prostate | | | |
2013 | A novel hydroxysuberamide derivative potentiates MG132-mediated anticancer activity against human hormone refractory prostate cancers - The role of histone deacetylase and endoplasmic reticulum stress | Chen Y.-C.; Huang W.-J.; Hsu J.-L.; Yu C.-C.; Wang W.-T.; JIH-HWA GUH | Prostate | 6 | 6 | |
2003 | A novel secobetulinic acid 3,4-lactone from Viburnum aboricolum | Ku Y.-L.; Rao G.V.; Chen C.-H.; Wu C.; JIH-HWA GUH ; SHOEI-SHENG LEE | Helvetica Chimica Acta | 15 | 12 | |
2014 | A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase i | Yu C.-C.; Pan S.-L.; Chao S.-W.; SHIH-PING LIU ; Hsu J.-L.; Yang Y.-C.; TSAI-KUN LI ; Huang W.-J.; JIH-HWA GUH | Biochemical Pharmacology | 29 | 28 | |
1996 | Ouabain-induced increases in resting tone of human hyperplastic prostate following repeated noradrenaline and electrical field stimulation | JIH-HWA GUH ; Ko F.-N.; SHIH-CHIEH CHUEH ; Lai M.-K.; Teng C.-M. | British Journal of Pharmacology | 8 | 8 | |
2008 | The p38 mitogen-activated protein kinase pathway plays a critical role in PAR2-induced endothelial IL-8 production and leukocyte adhesion | Pan S.L.; Tao K.Y.; JIH-HWA GUH ; Sun H.L.; Huang D.Y.; Chang Y.L.; Teng C.M. | Shock | 18 | 16 | |
2011 | Paclitaxel induces apoptosis through activation of nuclear protein kinase C-δ and subsequent activation of Golgi associated Cdk1 in human hormone refractory prostate cancer | Lu P.-H.; Yu C.-C.; Chiang P.-C.; Chen Y.-C.; Ho Y.-F.; FAN-LU KUNG ; JIH-HWA GUH | Journal of Urology | 16 | 14 | |
2018 | Para-toluenesulfonamide induces anti-tumor activity through Akt-dependent and -independent mTOR/p70S6K pathway: Roles of lipid raft and cholesterol contents | Hsu J.-L.; Leu W.-J.; LIH-CHING HSU ; SHIH-PING LIU ; Zhong N.-S.; JIH-HWA GUH | Frontiers in Pharmacology | 10 | 19 | |
1995 | Pharmacological evaluation of N-methyl-actinodaphnine, a new vascular α-adrenoceptor antagonist, isolated from Illigera luzonensis | JIH-HWA GUH ; Ko F.-N.; Yu S.-M.; Wu Y.-C.; Teng C.-M. | European Journal of Pharmacology | 19 | 16 | |
2003 | Pharmacological evaluation of several major ingredients of Chinese herbal medicines in human hepatoma Hep3B cells | Chou C.C.; Pan S.L.; Teng C.M.; JIH-HWA GUH | European Journal of Pharmaceutical Sciences | 85 | 76 | |
2020 | Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer | Wang Y.; Zhang L.; Wei Y.; Huang W.; Li L.; Wu A.-A.; Dastur A.; Greninger P.; Bray W.M.; Zhang C.-S.; Li M.; Lian W.; Hu Z.; Wang X.; Liu G.; Yao L.; JIH-HWA GUH ; Chen L.; Wang H.-R.; Zhou D.; Lin S.-C.; Xu Q.; Shen Y.; Zhang J.; Jurica M.S.; Benes C.H.; Deng X. | Cell Chemical Biology | 16 | 13 | |
2019 | Phosphodiesterase type 5 (PDE5) inhibitors sensitize topoisomerase II inhibitors in killing prostate cancer through PDE5-independent impairment of HR and NHEJ DNA repair systems | Chang J.-F.; Hsu J.-L.; Sheng Y.-H.; Leu W.-J.; Yu C.-C.; Chan S.-H.; Chan M.-L.; LIH-CHING HSU ; SHIH-PING LIU ; JIH-HWA GUH | Frontiers in Oncology | 11 | 13 | |
2020 | Phosphodiesterase Type 5 Inhibitors Synergize Vincristine in Killing Castration-Resistant Prostate Cancer Through Amplifying Mitotic Arrest Signaling | Hsu J.-L.; Leu W.-J.; LIH-CHING HSU ; Ho C.-H.; SHIH-PING LIU ; JIH-HWA GUH | Frontiers in Oncology | 11 | 9 | |
2012 | Pim-1 knockdown potentiates paclitaxel-induced apoptosis in human hormone-refractory prostate cancers through inhibition of NHEJ DNA repair | Hsu J.-L.; Leong P.-K.; Ho Y.-F.; LIH-CHING HSU ; Lu P.-H.; Chen C.-S.; JIH-HWA GUH | Cancer Letters | 23 | 17 | |
2005 | A potential role of YC-I on the inhibition of cytokine release in peripheral blood mononuclear leukocytes and endotoxemic mouse models | Pan S.-L.; JIH-HWA GUH ; Peng C.-Y.; Chang Y.-L.; Cheng F.-C.; Chang J.-H.; Kuo S.-C.; Lee F.-Y.; Teng C.-H. | Thrombosis and Haemostasis | 32 | 31 | |
2003 | Potentiation of tumor necrosis factor-α expression by YC-1 in alveolar macrophages through a cyclic GMP-independent pathway | Hwang T.-L.; Wu C.-C.; JIH-HWA GUH ; Teng C.-M. | Biochemical Pharmacology | 21 | 17 | |
2007 | Prazosin displays anticancer activity against human prostate cancers: Targeting DNA and cell cycle | Lin S.-C.; SHIH-CHIEH CHUEH ; Hsiao C.-J.; TSAI-KUN LI ; Chen T.-H.; Liao C.-H.; Lyu P.-C.; JIH-HWA GUH | Neoplasia | 61 | 58 | |
2012 | Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines | Chen C.-H.; Liao C.-H.; Chang Y.-L.; JIH-HWA GUH ; Pan S.-L.; Teng C.-M. | Cancer Letters | 54 | 49 | |
2012 | Pycnidione, a fungus-derived agent, induces cell cycle arrest and apoptosis in A549 human lung cancer cells | Che-Jen Hsiao; Shih-Hsin Hsiao; Wei-Lin Chen; JIH-HWA GUH ; George Hsiao; Yen-Ju Chan; Tzong-Huei Lee ; Chi-Li Chung | Chemico-Biological Interactions | 35 | 27 | |
2007 | Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways | Chen Y.-C.; Lu P.-H.; Pan S.-L.; Teng C.-M.; Kuo S.-C.; Lin T.-P.; Ho Y.-F.; Huang Y.-C.; JIH-HWA GUH | Biochemical Pharmacology | 58 | 59 | |