https://scholars.lib.ntu.edu.tw/handle/123456789/581968
標題: | Hepatitis B virus infection and metabolic syndrome: Fact or fiction? | 作者: | Wang C.-C. TAI-CHUNG TSENG JIA-HORNG KAO |
關鍵字: | Arteriosclerosis; Fatty liver; Hepatitis B virus; Insulin resistance; Lipid; Metabolic syndrome | 公開日期: | 2015 | 出版社: | Blackwell Publishing | 卷: | 30 | 期: | 1 | 起(迄)頁: | 14-20 | 來源出版物: | Journal of Gastroenterology and Hepatology (Australia) | 摘要: | Although hepatitis C virus infection is known to be linked with insulin resistance, dyslipidemia, and hepatic steatosis, the relationship between hepatitis B virus (HBV) infection and metabolic factors remains unclear. HBV infection is a health problem worldwide, especially in endemic regions such as Asia and Africa. It induces liver decompensation, cirrhosis, hepatocellualr carcinoma, and premature mortality. The prevalence of metabolic syndrome continues to increase in parallel with the epidemic of obesity, which is closely associated with the development of diabetes, cardiovascular disease, or even cancer. The systemic review shows that chronic HBV infection protects against instead of promotes fatty liver. The mechanism is possibly due to a lower frequency of dyslipidemia profile in patients with chronic HBV infection. The association of HBV with metabolic syndrome, insulin resistance, and the risk of arteriosclerosis is still inconclusive. In addition, obesity, diabetes, and metabolic syndrome may accelerate the progression of liver disease in patients with chronic HBV infection and synergistically induce cirrhosis or even hepatocellualr carcinoma development. ? 2014 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919595063&doi=10.1111%2fjgh.12700&partnerID=40&md5=bab49ec7dc384f55dbc4cc0961c2ae79 https://scholars.lib.ntu.edu.tw/handle/123456789/581968 |
ISSN: | 0815-9319 | DOI: | 10.1111/jgh.12700 | SDG/關鍵字: | lipid; arteriosclerosis; chronic hepatitis; diabetes mellitus; disease association; disease course; dyslipidemia; fatty liver; hepatitis B; Hepatitis B virus; human; insulin resistance; metabolic syndrome X; obesity; priority journal; Review; systematic review; Carcinoma, Hepatocellular; Cardiovascular Diseases; complication; hepatitis B; liver cirrhosis; Liver Neoplasms; metabolic syndrome X; obesity; prevalence; Carcinoma, Hepatocellular; Cardiovascular Diseases; Disease Progression; Hepatitis B, Chronic; Humans; Insulin Resistance; Liver Cirrhosis; Liver Neoplasms; Metabolic Syndrome X; Obesity; Prevalence |
顯示於: | 臨床醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。