Klebsiella pneumoniae peptidoglycan-associated lipoprotein and murein lipoprotein contribute to serum resistance, antiphagocytosis, and proinflammatory cytokine stimulation
Journal
The Journal of infectious diseases
Journal Volume
208
Journal Issue
10
Pages
1580
Date Issued
2013-11-15
Author(s)
Abstract
Peptidoglycan-associated lipoprotein (Pal), murein lipoprotein (LppA), and outer membrane protein A (OmpA) are dominant outer membrane proteins (OMPs) that are released by gram-negative bacteria during sepsis. OMPs are implicated in the maintenance of cell envelope integrity. Here, we characterize the roles of these OMPs in pathogenesis during bacteremia caused by Klebsiella pneumoniae.
Subjects
Klebsiella pneumoniae; murein lipoprotein; outer membrane protein A; outer membrane proteins; peptidoglycan-associated lipoprotein
SDGs
Publisher
OXFORD UNIV PRESS INC
Type
journal article
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