https://scholars.lib.ntu.edu.tw/handle/123456789/627743
標題: | Serum C-reactive protein levels correlates better to metabolic syndrome defined by International Diabetes Federation than by NCEP ATP III in men | 作者: | MAO-SHIN LIN SHYANG-RONG SHIH HUNG-YUAN LI LEE-MING CHUANG TIEN-CHUN CHANG Wei, Jung-Nan Shieh, Gow-Jen Chien, Yu-Fen Hua, Cyue-Huei JUEY-JEN HWANG |
關鍵字: | C-reactive protein; metabolic syndrome; low density lipoprotein; International Diabetes Federation; National Cholesterol Education Program; CARDIOVASCULAR-DISEASE; INSULIN-RESISTANCE; BLOOD-PRESSURE; RISK; CHOLESTEROL; INTERLEUKIN-6; PREVALENCE; GLUCOSE; FAT | 公開日期: | 八月-2007 | 出版社: | ELSEVIER IRELAND LTD | 卷: | 77 | 期: | 2 | 起(迄)頁: | 286 | 來源出版物: | Diabetes research and clinical practice | 摘要: | The International Diabetes Federation (IDF) proposed a new definition for metabolic syndrome (MS) in 2005. We conducted this study to compare the association of MS by IDF and ATP III definition to various metabolic variables. In 2005, we enrolled 654 Chinese people in a screening program in Taiwan. Anthropometric and biochemical profiles, including high-sensitivity C-reactive protein (hsCRP), were measured. Serum hsCRP levels were higher in those with MS by IDF definition (2.4+/-1.9mg/l versus 1.3+/-1.4mg/l, p<0.0001). Serum hsCRP levels increase with the number of components of MS they met (p for trend<0.001). Serum LDL levels were higher in those with MS by IDF definition (131+/-39 versus 125+/-32, p<0.05) but not in those with MS by ATP III definition (p=0.2). Serum hsCRP levels correlate significantly to MS by ATP III definition, after adjusting for age, sex, smoking, body mass index, serum apolipoprotein A1 and LDL levels. Adding MS status by IDF definition in this model significantly increased model fitness in men (MS by IDF definition, partial r=0.18, p<0.05, MS by ATP III definition, partial r=0.12, p=0.071). In conclusion, IDF definition of MS has a stronger relationship with serum hsCRP than ATP III definition in men. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627743 | ISSN: | 0168-8227 | DOI: | 10.1016/j.diabres.2006.11.013 |
顯示於: | 醫學系 |
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