研究成果


第 1 到 46 筆結果，共 46 筆。

公開日期標題作者來源出版物scopusWOS全文
12024Integrating High-throughput Phenotypic Profiling and Transcriptomic Analyses to Predict the Hepatosteatosis Effects Induced by Per- and Polyfluoroalkyl SubstancesYU-SYUAN LUO ; Ying, Ren-Yan; Chen, Xsuan-Ting; Yeh, Yu-Jia; CHIA-CHENG WEI ; CHANG-CHUAN CHAN Journal of Hazardous Materials
22023Human health risk assessment from exposure to multiple sources of Hexabromocyclododecanes (HBCDs) in TaiwanLo, Shih Lin; Wang, Ren Der; Chen, Yi Ju; Hsu, Yuan Cheng; YU-SYUAN LUO ; GEN-SHUH WANG Sustainable Environment Research00
32023Dose-response formation of N7-(3-benzo[1,3]dioxol-5-yl-2-hydroxypropyl)guanine in liver and urine correlates with micronucleated reticulocyte frequencies in mice administered safrole oxideKUEN-YUH WU ; Wei, Yu-Tzu; YU-SYUAN LUO ; Shen, Li-Chin; Chang, Bao-Suei; Chen, Ya-Yin; Huang, Yan-Chi; Huang, Hui-Fen; Chung, Wen-Sheng; Chiang, Su-YinFood And Chemical Toxicology
42023Bayesian-Based Probabilistic Risk Assessment of Fipronil in Food: A Case Study in TaiwanYU-SYUAN LUO Toxics00
52023Simultaneous toxicokinetic studies of aristolochic acid I and II and aristolactam I and II using a newly-developed microdialysis liquid chromatography-tandem mass spectrometryChiang, Su-Yin; Wey, Ming-Tsai; YU-SYUAN LUO ; Shih, Wei-Chung; Chimeddulam, Dalaijamts; Hsu, Po-Chi; Huang, Hui-Fen; Tsai, Tung-Hu; KUEN-YUH WU Food and Chemical Toxicology00
62023Integrating high-throughput exposure assessment and in vitro screening data to prioritize endocrine-active potential and dietary risks of pesticides and veterinary drug residues in animal productsYU-SYUAN LUO ; Chiu, Zi-Yi; KUEN-YUH WU ; Hsu, Chao-ChengFood and Chemical Toxicology22
72023Study of urinary mercapturic acids as biomarkers of human acrylonitrile exposureKUEN-YUH WU ; Chia-Fang Wu; YU-SYUAN LUO ; Yu-Fang Huang; Shi-Nian Uang; Yen-Yi Lee; Su-Yin ChiangToxicology Letters00
82023Editorial: Endocrine-active substances in food: identification, evaluation, and controlYU-SYUAN LUO ; Ye, Xiaoqing; Yin, ShanshanFrontiers in Nutrition00
92022Reanalysis of Trichloroethylene and Tetrachloroethylene Metabolism to Glutathione Conjugates Using Human, Rat, and Mouse Liver in Vitro Models to Improve Precision in Risk CharacterizationValdiviezo, Alan; Brown, Grace E; Michell, Ashlin R; Trinconi, Cristiana M; Bodke, Vedant V; Khetani, Salman R; YU-SYUAN LUO ; Chiu, Weihsueh A; Rusyn, IvanEnvironmental Health Perspectives33
102022風險分析 進階篇: 第四章 計算毒理學吳焜裕 ; 蕭伊倫; 周韋均; 羅宇軒 ; 何文照; 蔡瑄庭; 林芬瑜; 林希偉; 吳敏華
112022Response Letter to Koivisto et al. 'Evaluating the Theoretical Background of STOFFENMANAGER® and the Advanced REACH Tool'Fransman, Wouter; Arnone, Mario; Borghi, Francesca; Cattaneo, Andrea; Cavallo, Domenico M; Cherrie, John W; Franken, Remy; Galea, Karen S; van der Haar, Rudolf; Heussen, Gerardus A H; Jensen, Keld A; Koponen, Milja; Koppisch, Dorothea; Kromhout, Hans; Luo,Yu-Syuan ; McNally, Kevin; Säämänen, Arto; Spinazzè, Andrea; van Tongeren, Martie; Vanoirbeek, Jeroen; Verpaele, Steven; Vetter, Daniel; Viegas, Susana; Warren, NickAnnals Of Work Exposures And Health33
122022Chemical and biological assessments of environmental mixtures: A review of current trends, advances, and future perspectivesLuo,Yu-Syuan ; Chen, Zunwei; Hsieh, Nan-Hung; Lin, Tzu-EnJournal of Hazardous Materials1010
132022Simultaneous toxicokinetics characterization of acrylamide and its primary metabolites using a novel microdialysis isotope-dilution liquid chromatography mass spectrometry methodYU-SYUAN LUO ; Chiang, Su-Yin; Long, Tai-Ying; Tsai, Tung-Hu; KUEN-YUH WU Environment International44
142021Characterization of primary glutathione conjugates with acrylamide and glycidamide: Toxicokinetic studies in Sprague Dawley rats treated with acrylamideYU-SYUAN LUO ; Long, Tai-Ying; Chiang, Su-Yin; KUEN-YUH WU Chemico-biological Interactions86
152021Utilizing ion mobility spectrometry-mass spectrometry for the characterization and detection of persistent organic pollutants and their metabolitesAly, Noor A.; Dodds, James N.; YU-SYUAN LUO ; Grimm, Fabian A.; Foster, MaKayla; Rusyn, Ivan; Baker, Erin S.Analytical and Bioanalytical Chemistry64
162021Prediction of Hepatic Drug Clearance with a Human Microfluidic Four-Cell Liver Acinus MicroPhysiology SystemCourtney Sakolish; Yu-Syuan Luo ; Alan Valdiviezo; Lawrence A. Vernetti; Ivan Rusyn; Weihsueh A. ChiuToxicology73
172021Analysis of per- and polyfluoroalkyl substances in Houston Ship Channel and Galveston Bay following a large-scale industrial fire using ion-mobility-spectrometry-mass spectrometryValdiviezo, Alan; Aly, Noor A.; Luo,Yu-Syuan ; Cordova, Alexandra; Casillas, Gaston; Foster, MaKayla; Baker, Erin S.; Rusyn, IvanJournal of Environmental Sciences1311
182021Quantitative Characterization of Population-Wide Tissue- and Metabolite-Specific Variability in Perchloroethylene Toxicokinetics in Male MiceDalaijamts, Chimeddulam; Cichocki, Joseph A; YU-SYUAN LUO ; Rusyn, Ivan; Chiu, Weihsueh AToxicological sciences : an official journal of the Society of Toxicology44
192021Quantitative in Vitro-to-in Vivo Extrapolation for Mixtures: A Case Study of Superfund Priority List PesticidesValdiviezo, Alan; Luo,Yu-Syuan ; Chen, Zunwei; Chiu, Weihsueh A; Rusyn, IvanToxicological sciences : an official journal of the Society of Toxicology88
202021Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risksAly, Noor A; Casillas, Gaston; YU-SYUAN LUO ; McDonald, Thomas J; Wade, Terry L; Zhu, Rui; Newman, Galen; Lloyd, Dillon; Wright, Fred A; Chiu, Weihsueh A; Rusyn, IvanJournal of exposure science & environmental epidemiology1717
212021Utilizing High-Throughput Screening Data, Integrative Toxicological Prioritization Index Score, and Exposure–Activity Ratios for Chemical Prioritization: A Case Study of Endocrine-Active Pesticides in Food CropsYU-SYUAN LUO ; Wu, Tsung HsienJournal of Agricultural and Food Chemistry55
222021Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytesYU-SYUAN LUO ; Chen Z.; Blanchette A.D.; Zhou Y.-H.; Wright F.A.; Baker E.S.; Chiu W.A.; Rusyn I.Food and Chemical Toxicology76
232021Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 TherapeuticsCharrez, Bérénice; Charwat, Verena; Siemons, Brian A; Goswami, Ishan; Sakolish, Courtney; YU-SYUAN LUO ; Finsberg, Henrik; Edwards, Andrew G; Miller, Evan W; Rusyn, Ivan; Healy, Kevin EFrontiers in pharmacology1113
242021Analysis of reproducibility and robustness of a human microfluidic four-cell liver acinus microphysiology system (LAMPS)Sakolish C.; Reese C.E.; YU-SYUAN LUO ; Valdiviezo A.; Schurdak M.E.; Gough A.; Taylor D.L.; Chiu W.A.; Vernetti L.A.; Rusyn I.Toxicology2421
252020Temporal and spatial analysis of per and polyfluoroalkyl substances in surface waters of Houston ship channel following a large-scale industrial fire incidentAly N.A.; YU-SYUAN LUO ; Liu Y.; Casillas G.; McDonald T.J.; Kaihatu J.M.; Jun M.; Ellis N.; Gossett S.; Dodds J.N.; Baker E.S.; Bhandari S.; Chiu W.A.; Rusyn I.Environmental Pollution2216
262020Rapid Characterization of Emerging Per- And Polyfluoroalkyl Substances in Aqueous Film-Forming Foams Using Ion Mobility Spectrometry-Mass SpectrometryYU-SYUAN LUO ; Aly N.A.; McCord J.; Strynar M.J.; Chiu W.A.; Dodds J.N.; Baker E.S.; Rusyn I.Environmental Science and Technology3324
272020In Vitro Bioavailability of the Hydrocarbon Fractions of Dimethyl Sulfoxide Extracts of Petroleum SubstancesYU-SYUAN LUO ; Ferguson K.C.; Rusyn I.; Chiu W.A.Toxicological Sciences98
282020PBPK modeling of impact of nonalcoholic fatty liver disease on toxicokinetics of perchloroethylene in miceDalaijamts C.; Cichocki J.A.; YU-SYUAN LUO ; Rusyn I.; Chiu W.A.Toxicology and Applied Pharmacology55
292019Modulation of tetrachloroethylene-associated kidney effects by nonalcoholic fatty liver or steatohepatitis in Male C57BL/6J MiceCichocki J.A.; YU-SYUAN LUO ; Furuya S.; Venkatratnam A.; Konganti K.; Chiu W.A.; Threadgill D.W.; Pogribny I.P.; Rusyn I.Toxicological Sciences55
302019Comparative analysis of Rapid Equilibrium Dialysis (RED) and solid phase micro-extraction (SPME) methods for In Vitro-In Vivo extrapolation of environmental chemicalsFerguson K.C.; YU-SYUAN LUO ; Rusyn I.; Chiu W.A.Toxicology in Vitro1615
312019Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of TetrachloroethyleneYU-SYUAN LUO ; Cichocki J.A.; Hsieh N.-H.; Lewis L.; Wright F.A.; Threadgill D.W.; Chiu W.A.; Rusyn I.Environmental health perspectives129
322019Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the MouseLewis L.; Borowa-Mazgaj B.; De Conti A.; Chappell G.A.; YU-SYUAN LUO ; Bodnar W.; Konganti K.; Wright F.A.; Threadgill D.W.; Chiu W.A.; Pogribny I.P.; Rusyn I.Chemical Research in Toxicology1111
332019Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc RelationshipsBlanchette A.D.; Grimm F.A.; Dalaijamts C.; Hsieh N.-H.; Ferguson K.; YU-SYUAN LUO ; Rusyn I.; Chiu W.A.Clinical Pharmacology and Therapeutics2523
342018Metabolism and Toxicity of Trichloroethylene and Tetrachloroethylene in Cytochrome P450 2E1 Knockout and Humanized Transgenic MiceYU-SYUAN LUO ; Furuya, Shinji; Soldatov, Valerie Y; Kosyk, Oksana; Yoo, Hong Sik; Fukushima, Hisataka; Lewis, Lauren; Iwata, Yasuhiro; Rusyn, IvanToxicological sciences : an official journal of the Society of Toxicology2422
352018Incorporation of the glutathione conjugation pathway in an updated physiologically-based pharmacokinetic model for perchloroethylene in miceDalaijamts, Chimeddulam; Cichocki, Joseph A; YU-SYUAN LUO ; Rusyn, Ivan; Chiu, Weihsueh AToxicology and applied pharmacology86
362018Effects of pirfenidone in acute and sub-chronic liver fibrosis, and an initiation-promotion cancer model in the mouseSeniutkin O.; Furuya S.; YU-SYUAN LUO ; Cichocki J.A.; Fukushima H.; Kato Y.; Sugimoto H.; Matsumoto T.; Uehara T.; Rusyn I.Toxicology and Applied Pharmacology3130
372018Comparative analysis of metabolism of trichloroethylene and tetrachloroethylene among mouse tissues and strainsYU-SYUAN LUO ; Hsieh N.-H.; Soldatow V.Y.; Chiu W.A.; Rusyn I.Toxicology1311
382018Characterization of inter-tissue and inter-strain variability of TCE glutathione conjugation metabolites DCVG, DCVC, and NAcDCVC in the mouseYU-SYUAN LUO ; Furuya S.; Chiu W.; Rusyn I.Journal of Toxicology and Environmental Health - Part A: Current Issues1816
392017Nonalcoholic fatty liver disease is a susceptibility factor for perchloroethylene-induced liver effects in miceCichocki J.A.; Furuya S.; YU-SYUAN LUO ; Iwata Y.; Konganti K.; Chiu W.A.; Threadgill D.W.; Pogribny I.P.; Rusyn I.Toxicological Sciences1213
402017Simultaneous detection of the tetrachloroethylene metabolites S-(1,2,2-trichlorovinyl) glutathione, S-(1,2,2-trichlorovinyl)-L-cysteine, and N-acetyl-S-(1,2,2-trichlorovinyl)-L-cysteine in multiple mouse tissues via ultra-high performance liquid chromatography electrospray ionization tandem mass spectrometryYU-SYUAN LUO ; Cichocki, Joseph A; McDonald, Thomas J; Rusyn, IvanJournal of toxicology and environmental health. Part A1412
412017Grouping of Petroleum Substances as Example UVCBs by Ion Mobility-Mass Spectrometry to Enable Chemical Composition-Based Read-AcrossGrimm F.A.; Russell W.K.; YU-SYUAN LUO ; Iwata Y.; Chiu W.A.; Roy T.; Boogaard P.J.; Ketelslegers H.B.; Rusyn I.Environmental Science and Technology2221
422017Impact of nonalcoholic fatty liver disease on toxicokinetics of tetrachloroethylene in miceCichocki J.A.; Furuya S.; Konganti K.; YU-SYUAN LUO ; McDonald T.J.; Iwata Y.; Chiu W.A.; Threadgill D.W.; Pogribny I.P.; Rusyn I.Journal of Pharmacology and Experimental Therapeutics1818
432016Pharmacokinetics and bioavailability of oral single-dose maleic acid in biofluids of Sprague-Dawley ratsCharlene Wu ; HSIN-CHANG CHEN ; YU-SYUAN LUO ; Chiang, Su-Yin; KUEN-YUH WU Drug metabolism and pharmacokinetics54
442015Study of urinary 2-{[2-(acetylamino-2-carboxyethyl]sulfanyl}butanedioic acid, a mercapturic acid of rats treated with maleic acidYU-SYUAN LUO ; Tsai, Hsin-Yun; HSIN-CHANG CHEN ; Charlene Wu ; Shen, Li-Ching; Chung, Wen-Sheng; Chiang, Su-Yin; KUEN-YUH WU Toxicology letters44
452015Synthesis, characterization and analysis of the acrylamide- and glycidamide-glutathione conjugatesYU-SYUAN LUO ; Long, Tai-Ying; Shen, Li-Ching; Huang, Shou-Ling; Chiang, Su-Yin; KUEN-YUH WU Chemico-biological interactions2220
462015Potential Association of Urinary N7-(2-Carbamoyl-2-hydroxyethyl) Guanine with Dietary Acrylamide Intake of Smokers and NonsmokersHuang, Chih-Chun Jean; Wu, Chia-Fang; Shih, Wei-Chung; YU-SYUAN LUO ; Chen, Ming-Feng; Li, Chien-Ming; Liou, Saou-Hsing; Chung, Wen-Sheng; Chiang, Su-Yin; KUEN-YUH WU Chemical research in toxicology1614